The Diabetic Foot & Charcot: Pathophysiology, Osteomyelitis, and Neuroarthropathy

Diabetes remains the leading cause of chronic wounds and non-traumatic lower-extremity amputations worldwide. The diabetic foot represents a complex interplay of neuropathy, vascular disease, biomechanical stress, infection, and metabolic dysfunction. Without early recognition and intervention, minor tissue injuries can rapidly progress to limb-threatening complications.

This episode explores the underlying pathophysiology of diabetic foot ulcers and Charcot neuroarthropathy, emphasizing how early diagnostic recognition and coordinated multidisciplinary care can prevent catastrophic outcomes. Faculty will discuss the mechanisms through which neuropathy alters protective sensation, how biomechanical forces contribute to tissue breakdown, and why Charcot deformity dramatically increases ulcer risk.

Participants will learn how to recognize early warning signs of diabetic foot pathology, implement effective offloading strategies, and determine when surgical stabilization or advanced therapies are necessary to preserve limb function and patient mobility.